“Estrogen is released into the bloodstream
and travels to the organs and tissues where it is needed.
Examples include pills, skin patches, gels, and sprays”.1

Umbrella
What may the Hormone Therapy and Systemic Therapy Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Systemic Hormone Therapy
  • Systemic Hormones
  • Systemic Therapy

Definition

What is systemic therapy?

DotS the definition of systemic therapy may vary. In FAQs: Hormone Therapy for Menopause – How Does Hormone Therapy Work? the American College of Obstetricians and Gynecologists’ definition is:

  • Systemic estrogen therapy. Estrogen is released into the bloodstream and travels to the organs and tissues where it is needed. Examples include pills, skin patches, gels, and sprays”.2

Options

What are some systemic therapy options?

In Menopause FAQs: Hormone Therapy for Menopause Symptoms – Q. What Is Hormone Therapy? the North American Menopause Society’s (NAMS) explain:

Hormone Therapy and Systemic Therapy“For hot flashes, hormones are given in pills, patches, sprays, gels, or a vaginal ring that deliver hormones throughout the body—known as systemic therapy”.3

SERMs

What are SERMs (Selective Estrogen Receptor Modulators)?

In Menopause FAQs: Hormone Therapy for Menopause Symptoms – Q. What Is Hormone Therapy? the NAMS also note:

“Another approach to systemic hormone therapy is a pill that combines conjugated estrogens and a compound known as a SERM (selective estrogen receptor modulator) that protects the uterus but is not a progestogen. Women who have had a hysterectomy (had their uterus removed) can use estrogen alone to control their hot flashes. Women who still have a uterus need to take a progestogen in addition to estrogen or the estrogen-SERM combination to protect against uterine cancer”.4

Health Care Provider

What if I choose to use systemic therapy?

If you choose to use systemic therapy, it may be in your best interest to also choose to talk to your health care provider about this. The NAMS explain:

“Systemic hormones are very effective for hot flashes and have other benefits, such as protecting your bones. They also can carry risks, such as blood clots and breast cancer”.5

Health Topics A-Z

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Links

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Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. FAQs: Hormone Therapy for Menopause – How Does Hormone Therapy Work? Last Updated: October 2021. Last Reviewed: August 2022 American College of Obstetricians and Gynecologists https://www.acog.org/womens-health/faqs/hormone-therapy-for-menopause Accessed: 12 December 2023
  2. FAQs: Hormone Therapy for Menopause – How Does Hormone Therapy Work? Last Updated: October 2021. Last Reviewed: August 2022 American College of Obstetricians and Gynecologists https://www.acog.org/womens-health/faqs/hormone-therapy-for-menopause Accessed: 12 December 2023
  3. Menopause FAQs: Hormone Therapy for Menopause Symptoms – Q. What Is Hormone Therapy? North American Menopause Society https://www.menopause.org/for-women/menopause-faqs-hormone-therapy-for-menopause-symptoms Accessed: 12 December 2023
  4. Menopause FAQs: Hormone Therapy for Menopause Symptoms – Q. What Is Hormone Therapy? North American Menopause Society https://www.menopause.org/for-women/menopause-faqs-hormone-therapy-for-menopause-symptoms Accessed: 12 December 2023
  5. Menopause FAQs: Hormone Therapy for Menopause Symptoms – Q. What Is Hormone Therapy? North American Menopause Society https://www.menopause.org/for-women/menopause-faqs-hormone-therapy-for-menopause-symptoms Accessed: 12 December 2023
Topic Last Updated: 12 December 2023 – Topic Last Reviewed: 12 December 2023

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