Hormone Therapy and Stroke

“ Hormone therapy might slightly increase
your risk of stroke or blood clots in the legs or lungs
(especially if taken in pill form)”.1

Umbrella
What may the Hormone Therapy and Stroke Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Cardiovascular Disease
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Stroke

Cardiovascular Disease

What is cardiovascular disease (CVD)?

DotS the definition of CVD may vary. In Cardiovascular Heart Disease the British Heart Foundation’s (BHF) definition is:

“Cardiovascular disease (CVD), also called heart and circulatory disease, is an umbrella name for conditions that affect your heart or circulation. These include high blood pressure, stroke and vascular dementia”.2

Stroke

What is a stroke?

DotS the definition of a stroke may vary. The American Stroke Association’s definition is:

“A stroke occurs when a blood vessel that carries oxygen and nutrients to the brain is either blocked by a clot or bursts (or ruptures). When that happens, part of the brain cannot get the blood (and oxygen) it needs, so it and brain cells die”.3

Primary Ovarian Insufficiency and Premature or Early Menopause

Is HT recommended for women with primary ovarian insufficiency and premature or early menopause?

On page one in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement, published 07 July 2022, the North American Menopause Society (NAMS) explain:

  • “Women with primary ovarian insufficiency and premature or early menopause have higher risks of bone loss, heart disease, and cognitive or affective disorders associated with estrogen deficiency. It is recommended that hormone therapy can be used until at least the mean age of menopause unless there is a contraindication to its use”.4

Risk

What is the risk of stroke associated with HT?

On page one in Deciding About Hormone Therapy Use: Potential Benefits, published July 2022, the NAM explain:


Hormone Therapy and Stroke“As with all medications, HT is associated with some potential risks. For healthy women with bothersome hot flashes aged younger than 60 years or within 10 years of menopause, the benefits of HT generally outweigh the risks. Hormone therapy might slightly increase your risk of stroke or blood clots in the legs or lungs (especially if taken in pill form)”.5

In Menopausal Hormone Therapy, Heart Disease and Stroke the European Menopause and Andropause Society note:

  • “MHT may confer a small risk of stroke, more so with oral than with transdermal estrogen”.6

Chronic Disease

Is HT recommended for the prevention of stroke?

On page four in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “HRT should not be recommended for the primary or secondary prevention of chronic disease in women experiencing the menopause in keeping with national and international guidelines”.7

Health Care Provider

If I choose to use HT what is my risk of stroke?

Different women who choose to use HT can have different risks of stroke. It may therefore be in your best interest to also choose to talk to your health care provider about this.

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause another of the recommendations is:

  • “The decision whether to take HRT, the dose and duration of its use should be made on an individualised basis after discussing the benefits and risks with each patient. This should be considered in the context of the overall benefits obtained from using HRT including symptom control and improving quality of life as well as considering the bone and cardiovascular benefits associated with HRT use”.8

Health Topics A-Z

Where may I find Health Topics A-Z related to Hormone Therapy and Stroke?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

Where may I find Links related to Hormone Therapy and Stroke?

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Links

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New or Updated

  1. 5 Critical Steps To Help Prevent A Stroke
  2. 7 Things You Can Do To Prevent A Stroke
  3. About Stroke
  4. BMS TV: Bioidentical Hormones
  5. BMS TV: Coronary Heart Disease (CHD)
  6. BMS TV: Hormone Replacement Therapy (HRT)
  7. Bioidentical Hormones: Are They Safer?
  8. Blood Clots
  9. Cardiovascular Diseases
  10. Consumer Health: Menopause, Hormone Replacement Therapy and Heart Health
  11. Consumer Health: Stroke Awareness
  12. Deciding About Hormone Therapy
  13. Deciding About Hormone Therapy Use
  14. Dr Louise Newson: The Truth About the Menopause & HRT
  15. Family History
  16. Find A Menopause Practitioner [United States and Other]
  17. Find An AMS Doctor [Australasian Menopause Society i.e. Australia and New Zealand]
  18. Find Your Nearest BMS Menopause Specialist [British Menopause Society]
  19. Guidance on Menopausal Hormone Therapy
  20. HRT – Types, Doses and Regimens
  21. HRT: Benefits and Risks
  22. Healthy Lifestyle
  23. Heart Disease and Stroke In Women
  24. Hormone Replacement Therapy (HRT)
  25. Hormone Replacement Therapy (HRT): Alternatives To Hormone Replacement Therapy (HRT)
  26. Hormone Replacement Therapy (HRT): Benefits and Risks of Hormone Replacement Therapy (HRT)
  27. Hormone Therapy: Is It Right for You?
  28. Hot Flashes
  29. Hot Flashes: What Can I Do? [+ Video: What Are the Signs and Symptoms of Menopause?]
  30. Hypertension
  31. I Forgot To Ask the Doctor – E9: The Menopause: Can Every Woman That Wants It Have HRT?
  32. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video: Is HRT Bad for You?]
  33. Learning To Cope With Hot Flashes
  34. Let’s Talk About Perimenopause
  35. Life’s Essential 8
  36. Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video]
  37. Mayo Clinic Minute: How Lifestyle Changes May Help Manage Menopause Symptoms [+ Video]
  38. Mayo Clinic Minute: What Women Need To Know About Stroke [+ Video]
  39. Mayo Clinic Q and A: 21st Century Stroke Prevention Strategies
  40. Menopausal Hormone Therapy
  41. Menopausal Hormone Therapy and Venous Thromboembolism
  42. Menopausal Hormone Therapy, Heart Disease and Stroke
  43. Menopause
  44. Menopause
  45. Menopause Management: Hormone Replacement Therapy (HRT) – Cardiovascular Disease & HRT
  46. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
  47. Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
  48. Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
  49. Menopause Patient Information [Videos] 4. The Different Types of HRT
  50. Menopause Patient Information [Videos] 5. Lifestyle Advice In Menopause & Perimenopause
  51. Menopause Preparedness Toolkit Video Series: Common Conditions Associated With Menopause and Midlife
  52. Menopause Preparedness Toolkit Video Series: Lifestyle Tips for Menopause Wellness
  53. Menopause Preparedness Toolkit: A Woman’s Empowerment Guide
  54. Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
  55. Menopause Treatments: What Works, What Doesn’t
  56. Menopause and Heart Disease
  57. Menopause and Women’s Health
  58. Menopause and Your Health
  59. Menopause, Perimenopause, Hormone Therapy and Other Treatments With Madelyn Butler, MD [Podcast]
  60. Menopause: Diagnosis and Management – Information for the Public: Benefits and Risks of HRT – Heart Disease and Stroke (Cardiovascular Disease) [NICE Guideline]
  61. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  62. Menopause: Understanding the Changes and Finding Relief | Dr Susan Davis | The Proof Podcast EP 256
  63. National Center for Complementary and Integrative Health: Herbs At A Glance
  64. National Center for Complementary and Integrative Health: How Safe Is This Product or Practice?
  65. Natural Remedies To Help Manage Perimenopause Symptoms
  66. Natural Therapies & Supplements
  67. Navigating Menopause: Expert Insights and Solutions | Dr Susan Davis | The Proof Podcast EP 245
  68. Non-Estrogen Treatments for Menopausal Symptoms
  69. Nonhormone Treatments for Hot Flashes and Night Sweats
  70. Perimenopause
  71. Postmenopause
  72. Preventing Cardiovascular Disease
  73. Q&A: Health Changes During Menopause Associated With Increased Cardiovascular Risk
  74. Read My Lips
  75. Revised Global Consensus Statement on Menopausal Hormone Therapy
  76. Staying Healthy During and After Menopause
  77. Stroke
  78. Stroke
  79. Stroke
  80. Stroke
  81. Stroke.org [American Stroke Association]
  82. The 2023 Nonhormone Therapy Position Statement of The North American Menopause Society
  83. The Menopause: After the Menopause
  84. The Truth About Menopause Supplements | Dr Sarah Berry
  85. Therapy for the Effects of Menopause
  86. Tips To Help Manage Menopause Symptoms
  87. Types of Hormone Therapy
  88. Using Natural Therapies In the Menopause Transition – Webinar
  89. Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
  90. Video Series-2023: Menopause and Heart Disease
  91. Video Series-2023: NAMS 2023 Nonhormone Therapies Position Statement for Bothersome Menopause Symptoms
  92. Video Series-2023: New FDA-Approved Nonhormone Option for the Treatment of Hot Flashes
  93. Video: Leslie Cho, MD, Discusses CV Risks, Benefits of Menopausal Hormone Therapy
  94. Videos and Podcasts: Videos – Interviews: Heart Disease, Risk Factors of Developing Heart Disease, and Can I Take Hormones?
  95. Webinars: Previous – Hormones and Stroke: An Update on Treatment and Risk
  96. Webinars: Previous – Non-Hormonal Pharmacological Interventions For VMS
  97. What Is Cardiovascular Disease?
  98. Women & CVD
  99. World Heart Day [29 September]
    Hormone Therapy and Stroke
  100. World Stroke Day [29 October]
    Hormone Therapy and Stroke

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022. North American Menopause Society https://www.menopause.org/docs/default-source/press-release/ht-position-statement-release.pdf Accessed: 19 March 2024
  2. Cardiovascular Heart Disease. Page Last Reviewed: October 2019. British Heart Foundation https://www.bhf.org.uk/informationsupport/conditions/cardiovascular-heart-disease Accessed: 19 March 2024
  3. About Stroke. American Stroke Association https://www.stroke.org/en/about-stroke Accessed: 19 March 2024
  4. Deciding About Hormone Therapy: Potential Risks. July 2022. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 19 March 2024
  5. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022. North American Menopause Society https://www.menopause.org/docs/default-source/press-release/ht-position-statement-release.pdf Accessed: 19 March 2024
  6. Menopausal Hormone Therapy, Heart Disease and Stroke. 2022. European Menopause and Andropause Society
    https://emas-online.org/wp-content/uploads/2022/05/Menopausal-hormone-therapy-heart-disease-and-stroke.pdf Accessed: 19 March 2024
  7. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:3-4. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 19 March 2024
  8. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 19 March 2024
Topic Last Updated: 22 March 2024 – Topic Last Reviewed: 19 March 2024

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